LOOK WHO’S TALKING: CELLULAR COMMUNICATION

When it comes to our skin’s health have you ever considered the intricate world of cellular communication happening within your skin right now, and the impact - both positive and negative - it is having on your skin’s appearance at a deeper level?

Our skin is a dynamic ecosystem of cells that constantly interact, adapt, and respond to various signals, all of which are vital for its integral health and vitality. At the heart of this complex system lies the incredible process of cellular communication. While healthy signals help our skin to understand where repair and renewal is required, at Orveda we are looking to combat the signals sent from the senescent cells within our skin, which can trigger inflammation and weaken our skin matrix.

CHEMICAL MESSENGERS: THE LANGUAGE OF CELLS

Cellular communication relies on various chemical messengers to carry vital signals between cells. Some of the key players are cytokines, growth factors, and neuropeptides. Cytokines, for instance, are essential for immune responses and wound healing. They signal immune cells to rush to the site of injury and initiate the healing process. Growth factors, on the other hand, promote cell division, collagen production and tissue repair. Neuropeptides help regulate various skin functions like blood flow and inflammation. As we age these chemical messengers become less efficient; leading to visible signs of ageing in our skin as repair and healing rates slow. Growth factor production decreases, and collagen production also slows down. This results in the formation of wrinkles, fine lines and loss of skin firmness.

SKIN SENESCENCE - THE NEGATIVE IMPACT OF CELLULAR COMMUNICATION

Senescent cells are unique in their communication capabilities as once they reach the end of their natural lifecycle they don’t die off when they should instead the often dubbed ‘zombie cells’ release signals that can be spread to the neighboring cells turning them into senescent cells too, further accelerating the process by which skin appears more aged. This matter has to be considered with attentiveness, as in a recent study it was found that senescent cells were going from 20% in young skins to 60% in aged skins.*

*From test on > 65 years old subjects, "Reversing the aging stromal phenotype prevents carcinoma initiation” AGING , April 2011, Vol.3 No.4, Lewis et.Al.